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Principal Scientist, Chemical Development
Who We Are: At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs. What We Do: Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X and Facebook. (*in collaboration with AbbVie) About the Role: Responsible for research and development, tech transfer and commercialization of drug substance processes, as well as oversight of batch manufacturing and regulatory document contribution through managerial and individual input. Provides project management for CMC programs or Chemical Development projects. Manages direct reports. _ Your Contributions (include, but are not limited to): Your Contributions (include, but are not limited to): Plans and manages projects. Represents Chemical Development on cross-functional teams. Maintains accountability for deliverables and progress on R&D and manufacturing plans for Chemical Development projects Independently designs, plans and executes activities towards the goals of one or more Chemical Development projects to support preclinical through commercial activities Supervises laboratory work and/or lab personnel and ensures safe laboratory practices Performs process R&D and optimizes synthetic routes Identifies and recommends approaches to novel ideas in Chemical Development Provides support for off-site synthesis, manufacturing activities and interaction with contractors Provides input into CMC regulatory documentation and supporting work May provide supervision of laboratory personnel and guidance for their professional development Contributes to development of policies and executes against department strategies Builds and enhances internal and external professional relationships Other duties as assigned Requirements: BS/BA in chemistry and 12+ years of experience in experience in pharmaceutical/process development field, including API manufacturing person in plant activities, Experience managing laboratory, maximizing productivity is desirable OR MS/MA in chemistry and 10+ years of similar experience noted above OR PhD in chemistry and 4+ years of similar experience noted above; may include postdoc experience OR Thorough understanding of organic chemistry and a well-developed understanding of process chemistry as well as current literature Excellent laboratory and productivity skills API Manufacturing experience Good understanding of cGMP requirements in API Demonstration of cross-functional understanding related to drug development Assimilates data and research findings outside of Neurocrine for application to new scientific projects Maintains broad knowledge of scientific principles and theories and possesses intellectual mastery of one or more scientific areas May develop an understanding of other areas and related dependencies Advanced knowledge and demonstrated ability working with / recommending a variety of laboratory equipment/tools Ability to work as part of and lead multiple teams Exhibits leadership skill and ability, typically leads lower levels and/or indirect teams Excellent computer skills Excellent interpersonal, communications, problem-solving, analytical thinking skills Sees broader picture, impact on multiple programs, teams and/or departments Ability to meet multiple deadlines across a variety of projects/programs, with a high degree of accuracy and efficiency Excellent project management skills #LI-OB1 Requirements: Neurocrine Biosciences is an EEO/Disability/Vets employer. We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description. _ The annual base salary we reasonably expect to pay is $130,800.00-$179,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a arenaflex of 30% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans. We are a top place to work. Neurocrine Biosciences was named one of the FORTUNE Best Workplaces in Biopharma™ 2025. We were also named a Great Place to Work® Certified company. ©2025 Fortune Media IP Limited. All rights reserved. Used under license. OUR VALUES: PASSION: We are driven and love what we do. We are committed to our goals and to making a difference. INTEGRITY: We do the right thing for patients and our community. We take accountability. We speak up. COLLABORATION: We trust one another. We are inclusive. We are respectful. We are transparent. Together we succeed. INNOVATION: We seek and create optimal solutions. TENACITY: We do not quit. We adapt. We accomplish what others cannot. Come join our team during this exciting time of growth and opportunities! Apply tot his job
